تأثيرالوجبات الغذائية القياسية والمنخفضة البروتين المحتوية على الصمغ العربي على الفئران المصابة بإرتفاع حمض يوريک الدم

نوع المستند : المقالة الأصلية

المؤلفون

1 جامعة عين شمس

2 کلية التربية النوعية - جامعة عين شمس

3 کلية الاقتصاد المنزلي-جامعة حلوان

المستخلص

Hyperuricemia is a common disorder that affects patients of all ages and genders. Gum Arabic (GA) is a complex polysaccharide , believed to be an excellent curative for hyperuricemia,The present study is aimed to investigate the effect of diets containing gum arabic on hyperuricemic rats. A specimen of forty nine albino rats were divided into two main groups. The first main group (7 rats) fed on basal diet (BD) as control negative group, the second main group (42 rats) treated with 30% fructose in drinking water for 6 weeks to induce hyperuricemia ,and treated with standard diet or low protein diet (LPD) plus gum arabic in different proportions (5% and 10%).The experiment lasted for 4 weeks.Groups which treated with standard or (LPD) containing 10% GA recorded the best results as decrement the % of body weight gain and kidney weight / body weight% as compared to the other groups with hyperuricemia. the best results in decreasing glucose and kidney functions which including serum uric acid, urea nitrogen and creatinine were recorded for the hyperuricemic group fed on a (LPD) containing 10% Gum arabic, followed by the group which suffer from hyperuricemia and treated with a standard diet containing 10% GA. Also feeding rats with hyperuricemia on a standard diet or (LPD) containing (5% and 10% GA) improved the lipid profile and the liver enzymes , as compared to the positive control groups. conculsion (LPD) plus to gum arabic improve both liver and kidney function, specially for rats suffering from hyperuriecemia.

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